Synthesis and primary screening of the antioxidant activity of some 4-thioxo- and 4-imino- thiazolidin-2-ones
نویسندگان
چکیده
منابع مشابه
Synthesis and Antimicrobial Activities of Some New Azetidin-2-ones and Thiazolidin-4-ones
Various (4-substituted) phenyl-3-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]propionylamido-1,3-thiazolidine-4-ones (3a-x) and 1-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]-propionylamido-3-chloro-4-(4-substituted)phenyl-azetidin-2-ones (4a-x) have been synthesised by the cyclocondensation of Schiff bases (2a-x) with thioglycolic acid and chloroacetyl chloride, respecti...
متن کاملSynthesis and Antimicrobial Activity of 1-Thiazolidin-4-ones
A new series of 2-(3-oxo-3-phenylpropanoyl)-3-(substituted aryl)-1-thiazolidin-4-ones has been synthesized by cyclocondensation of ketoanils (the condensation products of 2, 4-dioxo-4phenyl butanal with primary amines) with mercaptoacetic acid. The chemical structures of the synthesized compounds were elucidated by elemental analysis, molecular weight determination, and UV, IR, 1H, 13C and DEPT...
متن کاملSynthesis, Characterization and Anti-HIV Evaluation of Some Novel 2-[(substitutedphenyl/heteroaryl)imino]-3-phenyl-1,3-thiazolidin-4-ones
A series of novel 2-[(substituted phenyl/heteroaryl)imino]-3-phenyl-1,3-thiazolidin-4-ones (4a-g) were synthesized, structurally confirmed by elemental analysis, IR, H NMR, MS spectral analysis and further evaluated for their anti-HIV activity and cytotoxicity in MT-4 cell cultures infected with wild-type HIV-1 strain IIIB and HIV-2 strain ROD in comparison with azidothymidine (AZT) and dideoxy...
متن کاملSynthesis, in vitro anticancer and antioxidant activity of thiadiazole substituted thiazolidin-4-ones.
A series of novel 5-alkyl/aryl thiadiazole substituted thiazolidin-4-ones were synthesized by a two-step process. In the first step, 5-alkyl/aryl substituted 2-aminothiadiazoles were synthesized, which on reaction with substituted aromatic aldehydes and thioglycolic acid in the presence of dicyclohexylcarbodiimide afforded thiazolidin- 4-ones. All the compounds were synthesized in fairly good y...
متن کاملsynthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Farmatsevtychnyi zhurnal
سال: 2021
ISSN: 2617-9628,0367-3057
DOI: 10.32352/0367-3057.1.21.02